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Our Science Plan

To Beyond Celiac, a cure means real treatment options so those with celiac disease can live healthy lives and eat without fear.

We firmly believe that with a strategic approach to targeted research, an effective treatment or cure is possible by 2030. To accomplish that goal, we are laser-focused on addressing the many current barriers.

Barriers to a Cure for Celiac Disease

  • Celiac disease is poorly understood by the medical community
  • Limited support for early career scholars/researchers
  • Serious nature of the disease is underappreciated
  • Too many people remain undiagnosed
  • Lack of funding and strategic focus for research
  • Assumption that the gluten-free diet is enough

With your support, Beyond Celiac will be the catalyst for the next wave of practical celiac disease research efforts.

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Our Scientific Priorities

The large, diverse celiac disease community continues to suffer from high daily burdens in coping with the disease, and we need treatments and a cure. Beyond Celiac has crafted its science plan to change the future for the 3.2 million Americans living with this serious autoimmune disorder.

Evidence Generation

Highlighting the seriousness of celiac disease

Through Go Beyond Celiac and other initiatives, we are collecting and analyzing comprehensive data on the burden of celiac disease and gluten sensitivity. With this information, we can increase awareness and make a compelling case for larger investments from government agencies, pharmaceutical companies, biotech and more.

How we're collecting/analyzing data:

Patient Registry & Database
We have built, and continue to expand, a patient database and registry called Go Beyond Celiac.

Improving diagnosis rates and addressing regulatory barriers with NMQF
We have formed a partnership with the National Minority Quality Forum to unearth and address health disparities in celiac disease.

Coalition to accelerate clinical research in celiac disease
We’ve brought together biotech, pharma, and diagnostic industry, clinicians, and scientists to overcome patient barriers in clinical trials

Diversity and healthcare equity initiative with Takeda
We have formed a partnership with Takeda to identify and reduce disparities in celiac disease diagnosis and management, aiming to raise awareness and help minority patients participate in clinical trials.

Translational Research

Accelerating scientific progress toward a cure

We are funding promising research that quickly translates from scientific investigation to clinical use, speeding the development of treatments for patients.

Learn more about the innovative research we’re currently funding:

Early Career Grant Award to study CD8 T-cells in celiac disease

Racial and ethnic healthcare disparities in celiac disease diagnosis

Established Investigator Award to study the gut-brain connection

Research partnership with Janssen to prevent celiac disease

Awards to study RNA sequencing in celiac disease

Grant to look at a mass screening program

Brain fog study

Clinical Trials

Enabling faster approval of treatments

As the nation’s top recruiter for celiac disease clinical trials, we will continue educating our community about the importance of participating in trials. We will also work with pharmaceutical companies to ensure trials are designed with patient perspectives in mind.

Learn more about how we’re assisting clinical trials:

Our patient recruitment offerings

Clinical trials for celiac disease

Drug development pipeline

Beyond Celiac Investments

A venture philanthropy program accelerating the development of treatments and a cure

We will invest significant resources to identify promising treatments and, as the leading celiac disease patient advocate and clinical trial recruiter, accelerate their progress through our financial, scientific, business, and regulatory networks.

Our Science Team

Meet the team implementing our science plan.

Clinical Trials

Information on studies looking for participants. Find out if you qualify

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Watch a video interview with our CEO, Alice Bast, our former Chief Scientist and Strategy Officer, Salvo Alesci, MD, and news reporter Diana Rocco.

Celiac Straight Talk Podcast cover art

Listen to our Celiac Straight Talk Podcast episode on our science plan: Apple Podcasts · PlayerFM · Stitcher

celiac disease science plan infographic preview

Download the Beyond Celiac Science Plan infographic.

Recent Research News
09/10/2024
Endoscopy and biopsy not a big barrier to participating in celiac disease clinical trials, Beyond Celiac study finds
For those with celiac disease, an endoscopy and biopsy may not be a major barrier to participating in clinical trials and intestinal healing is an important result when celiac disease patients consider potential treatments, Beyond Celiac research finds.
Read Full Story

Our Science Partners

Beyond Celiac partners with pharmaceutical, health and biotech companies and organizations to advance our shared goals of unlocking celiac disease and accelerating a cure.

We embrace and leverage strategic partnerships and strong collaborations to advance our plan priorities, overcome challenges and maximize progress toward a cure.

OUR PARTNERS