Fatigue is often listed as a symptom of celiac disease and is frequently reported by patients.
Fatigue (tiredness) is a state of physical or mental weariness. Tiredness can be both a physical and mental symptom. Chronic tiredness can be a symptom of many different diseases or conditions, including autoimmune conditions such as celiac disease.
However, a 2018 study found that the link between fatigue and celiac disease has not been studied enough to be fully understood.
While fatigue may be a natural and transient part of life, in a chronic condition such as celiac disease, these symptoms are unrelieved by adequate sleep or rest. Once diagnosed, the fatigue suffered by celiac disease patients often improves with the gluten-free diet, though not always.